Have you ever wondered why we always recommend performing a diagnostic paracentesis on patients with cirrhosis when they are hospitalized? This is the study for…
Treatment of alcohol use disorder in patients with cirrhosis is essential. Here is one RCT assessing whether baclofen is a safe and effective option! https://bit.ly/3HXb9Ll
61 year old male with alcohol-related cirrhosis presents with severe ascites. He had a therapeutic paracentesis with improvement in his ascites and underwent a surveillance EGD which showed large varices that were then banded. The following day, he developed tachycardia, hypotension, and hematochezia. A nasogastric tube was placed to suction without blood return.
What is the most likely etiology of the bleed?
Primary sclerosing cholangitis (PSC) is a primary biliary disorder characterized by progressive destruction of bile ducts. In this post we will present the most classic microscopic findings of PSC, while discussing the challenges of making this diagnosis solely based on histology.
In a follow-up to an outstanding overview of NSBB therapy in liver disease, Part 2 of this series by Anahita Rabiee presents evidence in support of earlier use of NSBBs in cirrhosis. Read on!
In the first post from new LFN author Anahita Rabiee, we are gifted an authoritative review on the Whys and Hows of beta-blockade in decompensated cirrhosis! You definitely want to read this one!
In part 2 of our coagulopathy series, we take a deeper dive and learn the ways in which end-stage liver disease alters the body’s normal hemostatic mechanisms.
The first “7 Minutes with an Expert” post, featuring a discussion on the cardiac evaluation of patient’s with liver disease with Northwestern’s Dr. Lisa VanWagner.
A 5 month old FT baby boy presented with a five day history of abdominal distention, jaundice and was found to have significant ascites and elevated AFP. Laboratory evaluation was significant for hypoalbuminemia (albumin-1.8 g/dL), coagulopathy (INR-3.5) and elevated alpha-feto protein (23,300 ng/mL). Whole exome sequencing was non-diagnostic and he was diagnosed with cryptogenic cirrhosis. During his admission his ascites is refractory to both medical therapy and repeat paracentesis. He is listed for liver transplant. Of the following, what is the best predictor of post-transplant mortality and graft survival?
Our newest LFN Quick Tips infographic is on hepatopulmonary syndrome (HPS). We review important aspects in presentation, diagnosis, and management of one of the main pulmonary consequences of end-stage liver disease.