Pathology Pearls Post 8: Primary Sclerosing Cholangitis (PSC)

Primary sclerosing cholangitis (PSC) is a primary biliary disorder characterized by progressive destruction of bile ducts. In this post we will present the most classic microscopic findings of PSC, while discussing the challenges of making this diagnosis solely based on histology.

Pathology Pearls Post 7: Primary Biliary Cholangitis

Primary biliary cholangitis (PBC) is a chronic liver disorder caused by progressive bile duct destruction. In this post, we will present the characteristic histologic findings of PBC, as well as the key histologic differentials to keep in mind when working up a liver biopsy with portal-based inflammation.